Igitabo Cyuzuye Kuri Al-Aluminium Foil yo Gupakira imiti ya farumasi

Mu buhanga mu bya farumasi, gupakira ntabwo ari kontineri gusa - ni ikintu kigize gahunda yo gutanga imiti. Igipimo gikomeye cyo mu kanwa, harimo ibinini byoroshye cyane, capsules ya hygroscopique, hamwe na waferi yumye yumye, bihita bitakaza imbaraga iyo bihuye nibintu byo mu kirere mugihe cyo kubika.

Kugumana imbaraga zo kuvura mumyaka myinshi yikurikiranya bisaba kashe yumubiri idacogora. Inzitizi ndende ya aluminiyumu ikora nk'ibipimo bya zahabu kuri sisitemu yo gupakira blisteri ku isi hose, itanga imikorere ya zeru-permeability, ibishobora gutondekwa mu buryo bwa tekinike, hamwe no kubahiriza ibyemezo bya sterile bikenewe kugira ngo ibiyobyabwenge bikiza ubuzima bitangirika.

Kurinda Molecular Ihamye

Ibikoresho bya farumasi bifatika (APIs) nibintu byoroshye byimiti yibasiwe no kwangirika byihuse iyo bihuye nibidukikije bidateganijwe.

Ibidukikije byangiza ibidukikije bya farumasi

Imbaraga eshatu zibanze zo mu kirere zibangamira umutekano w’ibiyobyabwenge imbere mu cyuho:

• Hydrolytic Cleavage (Ingress )

• Kwangirika kwa Oxidative (Oxygene Permeation): Kwinjira kwa ogisijeni y’ibidukikije bitera urunigi rwisanzuye mu buryo bworoshye muri APIs zoroshye, bigatuma habaho ibicuruzwa bitangiza cyangwa uburozi.

• Kwangirika kwa Photolytike (Kumurika Umucyo): Fotone hirya no hino ya UV hamwe numucyo ugaragara byerekana ko ari umusemburo wo kuvugurura molekile, bigatera ibara ryihuse no gutakaza imbaraga za chimique.

Byinshi-Barrière Foil Matrix Ubwubatsi

Ibikoresho bya farumasi bifashisha ibice bibiri byibanze bya feri-barrière, buri kimwe kijyanye ninshingano zubukorikori zitandukanye.

Gusunika-Binyuze-Gupakira (PTP) Kubaka Amabati

Urupapuro rwa PTP rushyizweho kugirango rufungwe mu cyuho cyashushe cyangwa gikonje, gitanga inzitizi yuzuye mu gihe gikomeza ubushyuhe bukabije, butuma abarwayi basunika ibinini byoroshye mu gifuniko:

Inzitizi Yumwanya-mwinshi na Plastike-Yakozwe cyane

Iri gereranya ryuzuye ryubuhanga ryerekana impamvu inzitizi ndende ya aluminium foil iruta firime nziza cyane ya plastike ya blister hejuru yububiko bukomeye:

Porogaramu Zibanze Kurenza Imiti yo Gutanga Imiti Yambere

Ibikoresho byinshi-aluminiyumu foil iboneza byateguwe neza kugirango birinde uburyo butandukanye bwo gutanga imiti ivura:

Ibibazo

Q1: Niki gitera PTP yipfundikanya cyane kugirango ifunike mugihe cyo gupakira byihuse, kandi byakwirindwa gute?

. Igisubizo Dingang Metal irinda ibi ukoresheje ibyuma bisobekeranye neza kandi ugahuza umurongo uringaniza kugirango ukureho impande zombi, ukemeza neza ko ukoresha neza imiyoboro yapakiye.

Q2: Ese lacquers yubushyuhe ikoreshwa kumiti yimiti ifite umutekano kugirango ihure neza na dosiye yo mu kanwa?

Igisubizo: Yego. Imiti yose yo mu rwego rwa farumasi yerekana ubushyuhe ikozwe muri inert, idafite ubumara bwa polymers bwujuje ubuziranenge bwa farumasi yisi yose hamwe namabwiriza ya FDA 21 CFR § 175.300, kugirango FDA yubahirizwe . Buri cyiciro gikorerwa ibizamini byo gukuramo buri gihe kugirango habeho kwimuka kwa toxicologique.

Ikibazo cya 3: Nigute kuringaniza impagarara bitezimbere ibimenyetso bifatika byo gupakira?

Igisubizo: Kuringaniza impagarara bikuraho imihangayiko yimbere kurubuga rwa fayili, ikuraho inenge zisanzwe zimeze nkibisumizi hagati cyangwa imiraba yumurongo. Ibi bigera kumurongo mwiza cyane ( gutandukana <0.5 mm / m ), bigatuma habaho guhuza kimwe hejuru yikibaho kugirango wirinde micro-void idafunze.

Q4: Niki gitera urwungano ngogozi kumeneka nyuma yo gufunga ubushyuhe, kandi ni gute guhitamo amavuta bishobora kubikumira?

Igisubizo: Kumeneka akenshi biterwa na micro-pinholes cyangwa gukwirakwiza ubushyuhe butaringaniye mugihe cyo gufunga. Kugaragaza ibinure binonosoye cyane nka 8011 byemeza imiterere imwe yintete irwanya imiterere ya pinhole mugihe cyo gushushanya, mugihe ubushyuhe bwinshi bwumuriro wa aluminium butuma byihuta, ndetse nubushyuhe bwo gukwirakwiza kashe neza.

Q5: Ibikoresho byo gupakira aluminiyumu birashobora gukoreshwa nyuma yo gukoresha abaguzi?

Igisubizo: Aluminiyumu yuzuye ya PTP irashobora gutandukana kandi igakoreshwa neza mumigezi isanzwe yo gutunganya ibyuma. Kubice byinshi bikonje-imiterere ya Alu-Alu, gutunganya kabuhariwe birashobora gutandukanya firime ya polymer na aluminiyumu yibanze, bigatuma ibyuma byera cyane bisubirana kandi bigasubirwamo igihe kitazwi.

Umwanzuro

Kurinda imiti yimiti isaba ibikoresho byo gupakira bihuza imikorere ya barrière rwose hamwe nibikoresho byizewe. Mugihe firime ya plastike ikomeje kwibasirwa na gaze nubushuhe, ikora cyane inzitizi ndende ya aluminiyumu itanga inzitizi yumubiri irwanya kwangirika kw ibidukikije. Gufatanya nu ruganda rukomatanyirijwe hamwe nka Changzhou Dingang Metal Material Co., Ltd. rwemeza ko umurongo wawe wapakira wakiriye ubuziranenge bwibikoresho, kugenzura neza, no kugenzura niba amabwiriza yatanzwe kuva master roll kugeza kuri blister pack yuzuye.